日立7170和日立7600生化分析仪测定血糖结果的可比性分析

目的探讨不同检测系统之间血糖检测结果是否具有可比性。方法按照NCCLS EP9-A2文件的要求,以检测系统1（X）：日立7600全自动生化分析仪P1模块,迈克试剂,C.f.a.s.校准品和BIO-RAD质控品作为目标检测系统,检测系统2（Y1）和检测系统3（Y2）作为比较检测系统,在各检测系统中通过检测患者血葡萄糖水平来计算比较检测系统和目标检测系统之间的相对偏差（SE%）,以美国临床实验室修正法案（CLIA′88）规定的室间质量评价允许误差范围的1/2为标准,判断各检测系统间测定结果的临床可接受性。结果各检测系统间检测结果总体差异无统计学意义（P〉0.05）,检测结果明显相关（r2〉0.95）,测定结果偏倚评估临床可接受。结论血糖检测结果在该院3套检测系统间具有可比性。

Comparative analysis on results of blood glucose detected by Hitachi 7170 and Hitachi 7600 biochemical analyzers

Objective To discuss the comparability of blood glucose(GLU) results detected by different detection systems.Methods According to NCCLS document EP9-A2,3 biochemical testing systems including system 2-3(Y1-Y2,comparative testing systems) and system 1(X,targeted testing system,which was composed of Hitachi 7600 biochemical analyzer P1,maker reagents,C.f.a.s.calibrator and BIO-RAD quality control material),were used to obtain the correlation coefficient and the linear regression equation.The value of GLU in the patient′ s serum was detected by the three systems.Then the coefficient and the equation were used to evaluate the system bias between the comparative testing systems and the targeted testing system.The comparability of different testing systems was judged by half of the CLIA′ 88 standard.Results The variance analysis showed the results between various detection systems had no significant difference(P>0.05) and were significantly correlated(r2>0.95).The results showed good comparability.The deflection evaluation on detection results was clinically acceptable.Conclusion There is good comparability among the results of GLU detected by 3 different testing systems in our hospital.