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The coexistence of thyroid autoimmunity in children and adolescents with various allergic diseases
Authors:B Lindberg  U-B Ericsson  B Fredriksson  P Nilsson  CM Olsson  E Svenonius  S-A Ivarsson
Affiliation:Departments of Paediatrics, MalmöUniversity Hospital, University of Lund, Malmö, Sweden;Departments of Medicine, MalmöUniversity Hospital, University of Lund, Malmö, Sweden;Departments of Community Medicine, MalmöUniversity Hospital, University of Lund, Malmö, Sweden;Departments of Diagnostic Radiology, MalmöUniversity Hospital, University of Lund, Malmö, Sweden
Abstract:
The aim of our study was to investigate the coexistence of thyroid autoimmunity and allergic diseases. The prevalence of thyroid autoantibodies was studied in sera from 140 children with different kinds of allergic diseases, 370 11-13-y-old schoolchildren without allergic diseases serving as controls. The prevalence of thyroid peroxidase autoantibodies was found to be higher among the patients than in the control group, 11.4% vs 5.4% (p < 0:05). Ultrasound investigation identified autoimmune thyroiditis in 4.3% (6/140) of the series, which was later confirmed with fine needle aspiration in all six cases, four of which were unknown prior to the study. Our findings may be useful to alert clinicians that thyroid diseases may be superimposed on allergic children.
Keywords:Allergic disease    children    thyroid autoantibodies    thyroiditis    ultrasound
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