颅内室管膜下瘤22例临床分析

目的 研究颅内室管膜下瘤的临床特点、影像学特点及治疗. 方法 回顾性分析了北京天坛医院1996至2008年手术后经病理证实的22例颅内室管膜下瘤的临床特点、影像学表现、手术方法和预后.患者年龄5～54岁,男:女为13:9例.肿瘤位于侧脑室14例,位于第四脑室2例,位于额顶叶1例,脑干2例,桥小脑角1例,小脑1例,跨幕上下1例. 结果 全部病例经手术切除,全切除18例(幕上肿瘤15例和幕下肿瘤3例),部分切除4例(幕上下肿瘤1例和幕下肿瘤3例).病理类型包括单纯室管膜下瘤19例和混合性室管膜下瘤3例.随访肿瘤复发1例. 结论 颅内室管膜下瘤为一种罕见的良性颅内肿瘤,显微外科手术是主要治疗方法.肿瘤位于幕上者易获得完全切除;位于幕下者因边界不清、与周围重要结构粘连而常难以获得全切除.患者预后良好,肿瘤复发率低.

Intracranial subependymoma: clinical features and surgical management of 22 cases

Objective To study the clinical features, neuro-radiology and treatment of intracranial subepondymomas. Methods A total of 22 subependymomas were reviewed with regards to clinical presentation, neuro-imaging features, treatment, histopathological features and long-term follow-up. There were 13 males and 9 females with an age range of 5 to 54 years old. Fourteen tumors were located in lateral ventricles, 1 located on frontal-parietal lobe, 1 on mesencephalon, 2 on ports, 2 in fourth ventricle and 1 on cerebellum. One tumor was located in temporal lobe, mesencephalon, thalamus and pons. Results All tumors were surgically removed, including 18 totally removed (including 14 supra-tentorial and 4 infra-tentorial tumors) and 4 partially removed(including 1 supra- and infra-tentorial and 3 infra-tentorial tumors). During the follow-up, there was 1 recurrent case. Conclusion Intracranial subepondymoma is a rare benign tumor. And microsurgery represents the most effective therapy. Total resection can be expected for supra-tentorial tumors, but partial resection is often performed for infra-tentorial tumors. The prognosis is excellent and there is a rare tumor recurrence.