国产泮托拉唑治疗反流性食管炎的疗效

目的:比较国产泮托拉唑和进口奥美拉唑治疗反流性食管炎的疗效。方法:反流性食管炎患者共86例,随机分为2组,观察组46例给国产泮托拉唑40m g,早晚各1次,疗程8周;对照组40例给进口奥美拉唑20m g,早晚各1次,疗程8周。疗程结束后内镜复查。结果:泮托拉唑组和奥美拉唑组疗效分别为:治愈91.3%和87.5%,显效4.35%和7.5%,有效4.35%和5%(P>0.05);胃镜下反流性食管炎的疗效分别为:无效2.17%和2.5%,有效4.35%和2.5%,显效2.17%和5%,治愈率91.3%和90%(P>0.05)。结论:国产泮托拉唑能明显改善反流性食管炎的临床症状和镜下表现,疗效确切,使用安全。

The efficacy of domestic pantoprazole in the treatment of reflux esophagitis

Objective: To compare the efficacy of domestic pantoprazole capsule with imported omeprazole capsule in the treatment of reflux esophagitis(RE).Methods:86 patients witn RE were randomly divided into domestic pantoprazole capsule group with 40mg twice daily for 8 weeks or imported omeprazole capsule group with 20mg twice daily for 8 weeks.Results: The cure and effective rate of pantolazolegroup were 91.3% and 8.7%,respectively,those of omeprazole group were 87.5% and(12.5%),respectively.The endoscopic cure effective rate for pantoprazole group were 91.3.% and 6.53% respectively and for omeprazole group were 90% and 7.5% respectively.Conclusion: Domestic pantoprazole capsule are superior to to imported omeprazole capsule in the treatment of RE.