69例小儿中性粒细胞减少症的治疗方法及疗效分析

目的:分析小儿中性粒细胞减少症的治疗方法及疗效。方法:将2009年1月～2010年8月收治的小儿中性粒细胞减少症69例患儿随机分为A组(治疗组)35例和B组(对照组)34例。A组除常规应用抗病毒药物及支持治疗外,加用甘露聚糖肽或利可君升白细胞药物治疗;B组常规应用抗病毒药物及支持治疗。比较两组治疗前后的白细胞总数、中性粒细胞绝对值及治愈率。结果:治疗组26例恢复正常,总有效率为74.3%;对照组20例恢复正常,总有效率为58.8%。两组比较P<0.01。结论:小儿粒细胞减少症是严重危害小儿健康的疾病,临床应以预防为主,合理使用抗生素;及早发现并采取针对病因的综合治疗方法可以避免对患儿造成严重损害。

The treatment method and curative effect of 69 children with neutropenia disease

Objective:To investigate the treatment method and curative effect of the children with neutropenia disease. Methods:Sixty-nine children with neutropenia disease treated in our hospital from January 2009 to August 2010 were chosen and randomly divided into group A(treatment group) with 35 cases and group B(control group) with 34 cases.The children in group A were taken routine use of antiviral drugs and supportive care plus Mannatide or Lee Jun-liter white blood cells treatmeny.The children in group B were used support routine use of antiviral drugs and treatment.The leukocytes and neutrophils for the two groups before and after treatment were compared.The cure rate for the two groups after treatment were also compared. Results:After treatment and intensive care,26 patients returned to normal neutrophils in the treatment group,the total effective rate was 74.3%,while 20 cases were normal in the control group,the total effective rate was 58.8%.There was significant difference between the two groups,P<0.01. Conclusion:Children neutropenia is a serious disease endangering the health of children,it should be based on clinical prevention,take rational use of antibiotics,early detection and early action for the cause of comprehensive treatment for treatment to avoid serious damage to the children.