| 犬颈动脉囊状动脉瘤模型的建立实验研究 |
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| 引用本文： | 张海霞,程英升,李明华.犬颈动脉囊状动脉瘤模型的建立实验研究[J].介入放射学杂志,2006,15(2):85-87. |
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| 作者姓名： | 张海霞 程英升 李明华 |
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| 作者单位： | 200233,上海交通大学附属第六人民医院放射科 |
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| 摘 要： | 目的探讨建立犬颈总动脉囊状动脉瘤模拟人体颅内动脉瘤的可行性。方法采用外科手术方法建立犬颈动脉囊状侧壁动脉瘤模型。结果建立20条健康实验犬颈动脉囊状侧壁动脉瘤模型40枚,血管造影证实动脉瘤与载瘤动脉均通畅者有36枚,4枚动脉瘤腔自发性完全性闭塞,但颈总动脉均保持通畅,模型建立成功率为90.0%。结论犬颈总动脉囊状侧壁动脉瘤是模拟人体颅内动脉瘤的最佳模型之一。
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| 关 键 词： | 实验性动脉瘤 颈总动脉 动物模型 |
| 文章编号： | 1008-794X（2006）02-0085-03 |
| 收稿时间： | 2004-10-08 |
| 修稿时间： | 2004年10月8日 |
Models of experimental saccular aneurysms of carotid arteries in canine |
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| ZHANG Hai-xia,CHENG Ying-sheng,LI Ming-hua.Models of experimental saccular aneurysms of carotid arteries in canine[J].Journal of Interventional Radiology,2006,15(2):85-87. |
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| Authors: | ZHANG Hai-xia CHENG Ying-sheng LI Ming-hua |
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| Abstract: | Objective To study the availability by making experimental saccular aneurysm models of carotid arteries in canine similar to human intracranial aneurysms.Methods Twenty healthy canines with experimental saccular side-wall aneurysms of carotid arteries were created successfully by surgery. Results Forty experimental saccular side-wall aneurysms of carotid arteries were created successfully with 36 aneurysms and parent arteries maintaining patency with each other and four spontaneously occluded confirmed by angiography.Model successfurll rate reached 90%.Conclusions Experimental saccular side-wall aneurysms of carotid arteries in canines were one of best models created for simulating human intracranial aneurysms. |
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| Keywords: | Experimental intracranial aneurysm Carotid artery Animal model |
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