| 消炎合剂治疗慢性前列腺炎的实验研究 |
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| 引用本文： | 傅颖珺,戴群,刘立生.消炎合剂治疗慢性前列腺炎的实验研究[J].江西医学院学报,2006,46(6):63-65. |
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| 作者姓名： | 傅颖珺 戴群 刘立生 |
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| 作者单位： | [1]南昌大学医学院药理教研室,南昌330006 [2]南昌大学医学院功能中心,南昌330006 [3]南昌大学医学院新药研究室,南昌330006 |
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| 摘 要： | 目的探讨消炎合剂治疗慢性前列腺炎的药理作用及机制。方法以致炎动物大鼠和致血瘀动物兔为动物模型，观察消炎合剂抗炎和改善微循环的作用。结果消炎合剂能明显降低实验性大鼠炎症模型前列腺液中的白细胞数，什高卵磷脂小体密度，抑制纤维母细胞增生和炎细胞浸润，减轻腺体增生，增加和改善实验性兔瘀血模型微循环的血管管径，管径截面积，平均血流速度、平均血流量等，提示消炎合剂具有抗炎和改善徽循环的作用．结论消炎合剂有显著抑制实验性慢性前列腺炎的作用。
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| 关 键 词： | 消炎合剂 慢性前列腺炎 动物 实验 大鼠 兔 |
| 文章编号： | 1000-2294(2006)06-0063-03 |
| 收稿时间： | 04 13 2006 12:00AM |
| 修稿时间： | 2006年4月13日 |
Experimental Study on Chronic Prostatitis Treated by Dephlogisticate Mixture |
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| FU Ying-jun,DAI Qun,LIU Li-sheng.Experimental Study on Chronic Prostatitis Treated by Dephlogisticate Mixture[J].Acta Academiae Medicinae Jiangxi,2006,46(6):63-65. |
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| Authors: | FU Ying-jun DAI Qun LIU Li-sheng |
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| Institution: | a. Department of Pharmacology, b. Function Center, c. New Drug Laboratory, School of Medical Science, Nanchang University, Nanchang 330006, China |
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| Abstract: | Objective To explore the pharmacology action and the mechanism of Dephlogisticate Mixture(DM) on experimental chronic prostatitis.Methods The antiphlogistic and microcirculation-improving actions of DM were studied in the prostatitis rat model and blood stasis rabbit model.Results DM 0.6g/kg,1.2 g/kg significantly lowered the numbers of white blood cell,increased the density of lecithin corpuscle in secretion of prostates,inhabited the proliferation of fibroblasts and inflammatory infiltration in Xiaozhiling-induced chronic prostatic rats,and increased the caliber and transverse area of vessels,blood velocity and blood volume in rabbits.Conclusion DM could obviously inhibit experimental chronic prostatitis. |
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| Keywords: | dephlogisticate mixture(DM) chronic prostatitis animal experimental rat rabbit |
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