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| 莪术醇对人鼻咽癌细胞CNE2增殖、凋亡及周期的影响 | |
| 引用本文： | 何金年 姚东方 李杰恩. 莪术醇对人鼻咽癌细胞CNE2增殖、凋亡及周期的影响[J]. 中国耳鼻咽喉颅底外科杂志, 2011, 17(3): 171-174 |
| 作者姓名： | 何金年 姚东方 李杰恩 |
| 作者单位： | 广西医科大学第一附属医院耳鼻咽喉-头颈外科; |
| 基金项目： | 广西科学基金(编号:桂科基0779029) |
| 摘 要： | 目的 探讨莪术醇( curcumoI)在体外对人鼻咽癌CNE2细胞增殖、凋亡及周期的影响,为其临床治疗鼻咽癌提供理论依据.方法 不同浓度莪术醇作用于人鼻咽癌CNE2细胞后,用MTT法和流式细胞仪检测不同时间点鼻咽癌细胞CNE2的增殖、凋亡及周期分布.结果 莪术醇在体外明显抑制鼻咽癌CNE2细胞的增殖,且呈浓度和时间依赖... |
| 关 键 词： | 莪术醇 鼻咽癌 凋亡 细胞增殖 |
Effect of curcumol on proliferation, apoptosis and cell cycle of nasopharyngeal carcinoma CNE2 cells |
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| HE Jin-Nian,TAO Dong-Fang,LI Jie-En. Effect of curcumol on proliferation, apoptosis and cell cycle of nasopharyngeal carcinoma CNE2 cells[J]. Chinese Journal of Otorhinolaryngology-skull Base Surgery, 2011, 17(3): 171-174 | |
| Authors: | HE Jin-Nian TAO Dong-Fang LI Jie-En |
| Affiliation: | HE Jin-nian,YAO Dong-fang,LI Jie-en (Department of Otorhinolaryngology-Head and Neck Surgery,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China) |
| Abstract: | Objective To study the effect of curcumol on proliferation,apoptosis and cell cycle of nasopharyngeal carcinoma(NPC) cell line CNE2 in vitro and to investigate the feasibility of curcumol for the treatment of NPC.Methods Nasopharyngeal carcinoma CNE2 cells were treaded with curcumol of different concentrations.The cell proliferation inhibition rates,apoptosis ratios and cell cycle status at different time-points were detected with MTT and flow cytometry.Results The CNE2 proliferation was inhibited in dose-d... |
| Keywords: | Curcumol Nasopharyngeal neoplasm Apoptosis Cell multiplication |
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