乳化依托咪酯复合麻醉在无痛胃镜检查中的效果

目的探讨乳化依托咪酯复合麻醉在无痛胃镜检查中的效果。方法将300例进行无痛胃镜检查的患者分为芬太尼+异丙酚组(A组)、芬太尼+乳化依托咪酯组(B组)、乳化依托咪酯+芬太尼-咪达唑仑合剂组(C组),每组100例,观察患者的术中诱导时间、检查时间、苏醒时间、术中和术后不良反应。结果 C组患者诱导时间显著短于A组(P<0.01),B组、C组患者苏醒时间较A组显著延长(P<0.01),C组患者苏醒时间较B组显著延长(P<0.01)。B组、C组患者的呼吸暂停、低血压、注射痛发生率显著低于A组(P<0.01),B组、C组患者肌痉挛发生率显著高于A组(P<0.01,P<0.05),C组患者低血压发生率显著高于B组(P<0.01),C组患者肌痉挛发生率显著低于B组(P<0.05)。B组、C组患者术后头晕、注射痛发生率显著低于A组(P<0.01),C组患者术后恶心呕吐发生率显著低于A组、B组(P<0.01),C组患者注射痛发生率低于B组(P<0.01)。结论乳化依托咪酯复合芬太尼、咪达唑仑等用于无痛胃镜检查麻醉效果满意。

Effect of emulsifying etomidate combined anesthesia in painless gastroscopy

Objective To study the effect of emulsifying etomidate combined anesthesia in painless gastroscopy. Methods A total of 300 patients who had painless gastroscopy were divided into fentanyl and propofol group （group A）, fentanyl and etomidate group （ group B ） and etomidate, fentanyl and midazolam mixture group （ group C ）, with 100 patients in each group. The intraoperative indices such as induction time, inspection time, awakening time and so on of the patients were observed. Intraoperative adverse reactions and postoperative adverse reactions were also observed. Results The induction time of group C was lower significantly than that of group A（P 〈0.01 ）. The waking time was longer significantly in group B and group C compared with that of group A （ P 〈 0.01 ）, which was longer in group C compared with group B （ P 〈 0. 01 ）. The incidence of intraoperative apnea, injection pain and hypotension in group B and group C was obviously lower than that of group A（P 〈0. 01 ）. The incidence of muscle spasm in group B and group C was obviously higher than that in group A（P 〈 0. 01, P 〈0.05 ）. The hypotension incidence of patients in group C was obviously higher than that of group B （P 〈 0.01 ）. The incidence of muscle spasm in group C was obviously lower than that in group B （ P 〈 0.05 ）. The incidence of postoperative dizziness and pain at the injection site in group B and group C was obviously lower than that in group A （ P 〈 0.01 ）. The incidence of postoperative nausea and vomiting in group C was obviously less than that in group A and group B （ P 〈 0.01 ） ; the incidence of postoperative pain at the injection site in group C was obviously lower than that in group B （ P 〈 0. 01 ）. Conclusion The anesthesia effect of emulsifying etomidate combined with fentanyl and midazolam used in painless gastroscopy is satisfied.