| 止泻合剂的质量标准研究 |
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| 引用本文： | 王迅,周琴妹,吴旭彤,刘顺.止泻合剂的质量标准研究[J].中国实验方剂学杂志,2013,19(2):126-129. |
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| 作者姓名： | 王迅 周琴妹 吴旭彤 刘顺 |
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| 作者单位： | 江苏省中医院药学部,南京,210029 |
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| 摘 要： | 目的:建立止泻合剂的质量标准。方法:采用TLC对制剂中的主要药材进行定性鉴别,用HPLC测定芍药苷的含量。结果:用TCL鉴别止泻合剂中的秦皮、白芍、苍术、地锦草、木香等有效成分,方法简便易行、专属性强、重复性好,检出斑点清晰。芍药苷进样量在0.509～16.31 mg.L-1,线性关系良好,平均加样回收率为96.79%,RSD 1.7%(n=6)。结论:所建立的TLC和HPLC方法简便,专属性强,重复性好,可用于止泻合剂的质量控制。
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| 关 键 词： | 止泻合剂 芍药苷 TLC法 HPLC |
| 收稿时间： | 2012/7/12 0:00:00 |
Studies on Quality Specification of Zhixieheji |
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| WANG Xun,ZHOU Qin-mei,WU Xu-tong and LIU Shun.Studies on Quality Specification of Zhixieheji[J].China Journal of Experimental Traditional Medical Formulae,2013,19(2):126-129. |
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| Authors: | WANG Xun ZHOU Qin-mei WU Xu-tong and LIU Shun |
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| Institution: | Department of Pharmacy, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing 210029, China;Department of Pharmacy, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing 210029, China;Department of Pharmacy, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing 210029, China;Department of Pharmacy, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing 210029, China |
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| Abstract: | Objective: To establish the quality specification of Zhixieheji. Method: TCL method to identify the active ingredient of Zhixieheji of Cortex Fraxini, Paeoniae Radix, Atractylodes Lancea, Euphorbiae Humifusae, Radix Aucklandiae. The method is simple, specific, and reproducible; detection spots were clear. Of paeoniflorin in the injection volume 0.509-16.31 mg· L-1, and linear range of the relationship is good. The average recovery was 96.79%, RSD was 1.7% (n=6). Conclusion: The method is simple, efficient, sensitive and can be applied to quality control of Zhixieheji. |
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| Keywords: | Zhixieheji paeoniflorin TLC HPLC |
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