| 多指标正交试验法优选温胃阿亚然及片的提取工艺 |
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| 引用本文： | 毛艳,顾政一,贺金华,蔡晓翠,康雨彤,严欢,戎晓娟.多指标正交试验法优选温胃阿亚然及片的提取工艺[J].中国实验方剂学杂志,2013,19(4):53-56. |
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| 作者姓名： | 毛艳 顾政一 贺金华 蔡晓翠 康雨彤 严欢 戎晓娟 |
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| 作者单位： | 石河子大学药学院, 新疆 石河子 832002;新疆维吾尔自治区药物研究所, 乌鲁木齐 830004;新疆维吾尔自治区药物研究所, 乌鲁木齐 830004;新疆维吾尔自治区药物研究所, 乌鲁木齐 830004;新疆维吾尔自治区药物研究所, 乌鲁木齐 830004;新疆维吾尔自治区药物研究所, 乌鲁木齐 830004;新疆维吾尔自治区药物研究所, 乌鲁木齐 830004;新疆维吾尔自治区药物研究所, 乌鲁木齐 830004 |
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| 基金项目： | 新疆维吾尔自治区重大科技专项(201130105-4) |
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| 摘 要： | 目的:优选温胃阿亚然及片的提取工艺。方法:以芦荟苷、芦荟大黄素、总葫芦素含量和浸膏得率的综合评分为指标,采用L9(34)正交设计考察乙醇体积分数、提取次数及加醇量对温胃阿亚然及片提取工艺的影响。结果:最佳提取工艺为加15倍量80%乙醇提取3次,每次1 h。结论:优选的提取工艺简单、可行,可用于该制剂的工业化生产。
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| 关 键 词： | 温胃阿亚然及片 提取工艺 正交试验 芦荟苷 芦荟大黄素 总葫芦素 |
| 收稿时间： | 2012/9/26 0:00:00 |
Optimization of Extraction Technology for Wenwei Ayaranji Tablets by Multi-index Orthogonal Test |
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| MAO Yan,GU Zheng-yi,HE Jin-hu,CAI Xiao-cui,KANG Yu-tong,YAN Huan and RONG Xiao-juan.Optimization of Extraction Technology for Wenwei Ayaranji Tablets by Multi-index Orthogonal Test[J].China Journal of Experimental Traditional Medical Formulae,2013,19(4):53-56. |
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| Authors: | MAO Yan GU Zheng-yi HE Jin-hu CAI Xiao-cui KANG Yu-tong YAN Huan and RONG Xiao-juan |
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| Institution: | College of Pharmacy, Shihezi University, Shihezi 832002, China;The Xinjiang Institute of Materia Medic, Urumqi 830004, China;The Xinjiang Institute of Materia Medic, Urumqi 830004, China;The Xinjiang Institute of Materia Medic, Urumqi 830004, China;The Xinjiang Institute of Materia Medic, Urumqi 830004, China;The Xinjiang Institute of Materia Medic, Urumqi 830004, China;The Xinjiang Institute of Materia Medic, Urumqi 830004, China;The Xinjiang Institute of Materia Medic, Urumqi 830004, China |
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| Abstract: | Objective: To optimize extraction process of Wenwei Ayaranji tablets. Method: With the content of aloin,aloe-emodin,total cucurbitacin and extract yield as indexes,extraction technology of Wenwei Ayaranji tablets was optimized by orthogonal design by ethanol concentration,extraction times and ethanol amount. Result: Optimum extraction technology was as following:extracted 3 times with 15 times the amount of 80% ethanol,1 h each time. Conclusion: This optimized extraction technology was simple and feasible,it could be used for industrial production of the preparation. |
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| Keywords: | Wenwei Ayaranji tablets extraction process orthogonal test aloin aloe-emodin total cucurbitacins |
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