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| 独藤丸质量标准研究 | |
| 引用本文： | 谢暕,赵庆华,巩伟. 独藤丸质量标准研究[J]. 中国实验方剂学杂志, 2013, 19(4): 143-145 |
| 作者姓名： | 谢暕 赵庆华 巩伟 |
| 作者单位： | 1. 山东省交通医院,济南,250031 2. 济南军区联勤部药品仪器检验所,济南,250022 |
| 摘 要： | 目的:建立独藤丸质量标控制方法,为进一步扩大应用提供参考.方法:采用薄层色谱法(TLC)对独藤丸中独活、桑寄生、茯苓、甘草药材进行定性鉴别；采用高效液相色谱法(HPLC)测定独藤丸中蛇床子素的含量.结果:TLC定性鉴别斑点清晰,分离度好,色谱特征明显；HPLC测定蛇床子素20 ～ 200 mg· mL-1呈良好的线性关系(r=0.999 7,n=5),平均回收率为99.57％,RSD 2.309％.结论:方法简便、可靠、专属性强、重复性好、方法准确,可用于独藤丸的质量控制. |
| 关 键 词： | 独藤丸 薄层色谱法 高效液相色谱法 蛇床子素 质量标准 |
| 收稿时间： | 2012-07-07 |
Study on Quality Specification of Duteng Pills |
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| XIE Jian,ZHAO Qing-hua and GONG Wei. Study on Quality Specification of Duteng Pills[J]. China Journal of Experimental Traditional Medical Formulae, 2013, 19(4): 143-145 | |
| Authors: | XIE Jian ZHAO Qing-hua GONG Wei |
| Affiliation: | Traffic Hospitals in Shandong Province, Ji'nan 250031, China;Institute for Drug and Instrument Control, Joint Logistics Department of the Jinan Military Region, Ji'nan 250022, China;Institute for Drug and Instrument Control, Joint Logistics Department of the Jinan Military Region, Ji'nan 250022, China |
| Abstract: | Objective: To establish a method for the quality control of Duteng pills. Method: Pubescent angelica, Loranthus parasiticus, Poria cocos, Glycyrrhiza uralensis were identified by thin-layer chromatography (TLC). The osthole of Duteng pills was determind by HPLC. Result: The characteristic for identification by TLC was distinct. The linear correlation of osthole was good in the range of 20-200 mg·L-1 (r=0.999 7) (n=5) and the recovery was 99.57% (RSD 2.309%). Conclusion: The method is convenient and reliable with good specifity and reproducibility. It can be used for the quality control of Duteng pills. |
| Keywords: | Duteng pills TLC HPLC osthole quality specification |
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