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HPLC测定苍苓止泻口服液中绿原酸含量
引用本文:李翔,刘皈阳,马建丽,周亮,黄欣欣. HPLC测定苍苓止泻口服液中绿原酸含量[J]. 中国实验方剂学杂志, 2013, 19(2): 121-123
作者姓名:李翔  刘皈阳  马建丽  周亮  黄欣欣
作者单位:解放军总医院第一附属医院药剂药理科,北京,100048
摘    要:目的:建立HPLC测定苍苓止泻口服液中绿原酸的含量。方法采用高效液相色谱法,色谱柱为Agilent Eclipse XDB-C18,流动相为甲醇-0.5%冰醋酸溶液(20∶80),流速1.0 mL.min-1,检测波长327 nm,室温。结果:绿原酸浓度在0.021 84~0.436 8μg与峰面积线性关系良好,平均回收率为100.97%,RSD 2.10%(n=6)。结论:该方法简便、快速、准确、可靠,可用于苍苓止泻口服液中绿原酸的含量测定。

关 键 词:苍苓止泻口服液  绿原酸  高效液相色谱法  含量测定
收稿时间:2012-08-13

Determination of Chlorogenic Acid in Cangling Zhixie Oral Solution by HPLC
LI Xiang,LIU Gui-yang,MA Jian-li,ZHOU Liang and HUANG Xin-xin. Determination of Chlorogenic Acid in Cangling Zhixie Oral Solution by HPLC[J]. China Journal of Experimental Traditional Medical Formulae, 2013, 19(2): 121-123
Authors:LI Xiang  LIU Gui-yang  MA Jian-li  ZHOU Liang  HUANG Xin-xin
Affiliation:Department of Pharmacy, First Affiliated Hospital of PLA General Hospital, Beijing 100048, China;Department of Pharmacy, First Affiliated Hospital of PLA General Hospital, Beijing 100048, China;Department of Pharmacy, First Affiliated Hospital of PLA General Hospital, Beijing 100048, China;Department of Pharmacy, First Affiliated Hospital of PLA General Hospital, Beijing 100048, China;Department of Pharmacy, First Affiliated Hospital of PLA General Hospital, Beijing 100048, China
Abstract:
Keywords:Cangling Zhixie oral solution  chlorogenic acid  HPLC  determination
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