43例子痫临床诊治分析

目的 探讨子痫发病的临床特点、分娩时机及子痫对母儿的影响,提高临床对该病的认识和处理能力。方法 对2008-01～2012-12我院收治的43例子痫临床资料进行分析。结果 子痫发生率3.9‰,以产前子痫为主,占86.1%,无系统产检37例,占86%,农村人口占74.4%。子痫母体并发症占74.4%,子痫患者围生儿结局与发病至终止妊娠的孕周有关,孕34周前发病者新生儿重度窒息、围生儿死亡率显著增加(P＜0.01),与子痫抽搐次数无关(P＞0.05)。子痫早产发生率53.5%,围生儿死亡率18.6%。抽搐控制后尽早终止妊娠,可降低新生儿重度窒息发生率。结论 子痫易致母体发生多种并发症,围生儿预后不良,子痫控制后及时终止妊娠,可降低新生儿重度窒息及围生儿死亡率。

Clinical Analysis of 43 Cases of Eclampsia

Objective Investigatement clinical features of eclampsia to improve the diagnosis and treatment. Methods 43 cases with eclampsia from January 2008 to December 2012 were retrospectively analyzed. Results Incidence of eclampsia was 3.9 %0. Among them, Prenatal eclampsia acceunted of 86%, and 37 cases have no system inpection accounting for 86% and 74.4% were from rural areas. Eclampsia perinatal outcome were associated with the gestational weeks. The rate of severe neonatal asphyxia and perinatal death were significantly increased when eclampsia happened before 34 weeks（P 〈0.01 ） ,but perinatal outcome were not associated with the times of seizures（P 〉0. 05 ）. Incidence of preterm delivery in eclampsia was 53.5% ;the rate of perinatal death was 18.6%. If we can early terminate of pregnancy after controlled seizures, the incidence of severe neonatal asphyxia will be reduced. Conclusions Eclampsia increase the rate of complications in mater and poor prognosis in newborn. Timely delivery after controlled seizures will reduce the incidence of perinatal death and severe asphyxia in newborn.