保乳手术与改良根治术治疗早期乳腺癌临床疗效比较

目的分析和比较保乳手术与改良根治术治疗早期乳腺癌的疗效。方法将我院2010年1月²012年1月收治的76例早期乳腺癌患者随机分为保乳手术组和改良根治术组,两组患者在手术后均根据实际情况进行综合治疗,对两组治疗效果、并发症、局部复发率及远处转移率进行比较和分析。结果保乳手术组患者出现上肢水肿1例;局部复发2例;远处转移2例,1例为肺转移,1例为骨转移。改良根治术组出现12例并发症,其中4例上肢水肿,8例切缘皮瓣缺血;局部复发1例;远处转移3例,1例骨转移,1例肺转移,1例肝转移。两组患者术后并发症发生率差异显著(p<0.05)。结论保乳手术具有创伤小、并发症少、恢复快、乳房外观效果好,可大大提高患者的生活质量,值得临床推广使用。

COMPARISON OF CLINICAL CURATIVE EFFECTS BETWEEN BREAST CONSERVING SURGERY AND MODIFIED RADICAL TREATMENT FOR EARLY BREAST CANCER SURGERY

Objective To compare curative effects of breast conserving surgery with modified radical treat- ment for early breast cancer surgery. Methods 76 cases of early breast cancer selected from Jan. 2010 to Jan. 2012 in our hospital were randomly divided into breast conserving surgery group and modified radical treatment group. The comprehensive treatment was carried on according to the actual situation of two groups after surgery. The treatment effects, complications, the rates of local recurrence and distant metastasis of two groups were compared and analyzed. Results 1 case in breast conserving surgery group appeared with upper extremity edema, 2 cases with local recur- rence, 2 cases with distant metastasis, 1 case with pulmonary metastasis, 1 case with bone metastasis. 12 cases in modified radical treatment group appeared with complications, including g cases with upper limb edema, 8 cases with cut - edge flap ischemia, 1 case with local recurrence, 3 cases with distant metastasis, 1 case with bone metastasis, 1 case with pulmonary metastasis and 1 case with liver metastasis. There was a significant difference in postoperative complications of two groups （p 〈 0.05）. Conclusion Breast conserving surgery is advantageous for its small trau- ma, fewer complications, faster recovery and good breast appearance, which can greatly improve the quality of life of patients. So it is worth popularizating and using in clinic.