| 溃疡性结肠炎易感基因的研究进展 |
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| 引用本文： | 朱芳丽,刘蕾,张晓岚. 溃疡性结肠炎易感基因的研究进展[J]. 世界华人消化杂志, 2011, 0(21): 2201-2206 |
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| 作者姓名： | 朱芳丽 刘蕾 张晓岚 |
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| 作者单位： | 河北医科大学第二医院消化科河北省消化病重点实验室河北省消化病研究所; |
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| 摘 要： | 溃疡性结肠炎(ulcerative colitis,UC)是一种病因不明的肠道慢性炎症性疾病,目前较为一致的观点认为,UC是携带易感基因的个体在环境因素的作用下,自身免疫功能紊乱所引发的一种肠道非特异性炎症性疾病.其发病的种族地理差异、单卵双生子的高共患率和家族聚集现象,提示遗传因素在UC发病中起重要作用.目前已发现许...
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| 关 键 词： | 溃疡性结肠炎 基因 多态性 遗传易感性 |
Genes associated with susceptibility to ulcerative colitis |
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| Fang-Li Zhu,Lei Liu,Xiao-Lan Zhang. Genes associated with susceptibility to ulcerative colitis[J]. World Chinese Journal of Digestology, 2011, 0(21): 2201-2206 |
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| Authors: | Fang-Li Zhu Lei Liu Xiao-Lan Zhang |
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| Affiliation: | Fang-Li Zhu,Lei Liu,Xiao-Lan Zhang,Department of Gastroenterology,the Second Hospital of Hebei Medical University,Hebei Key Laboratory of Gastroenterology,Hebei Institute of Gastroenterology,Shijiazhuang 050000,Hebei Province,China |
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| Abstract: | Ulcerative colitis (UC) is a chronic intestinal inflammatory disease whose etiology is still unknown. It is widely believed that UC is a kind of non-specific inflammatory disease which is caused by environmental factors and autoimmune disorders in people who carry susceptibility genes. Epidemiologic data, such as familial aggregation, twin studies, and racial/ethnic differences in disease prevalence, indicate that there are genetic contributions to UC pathogenesis. In this article, we will review the recent... |
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| Keywords: | Ulcerative colitis Gene Polymorphism Genetic susceptibility |
| 本文献已被 CNKI 等数据库收录！ |
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