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荷瘤鼠乳腺癌组织的飞秒双光子荧光诊断
引用本文:苗绪红,李迎新,张红雨,魏赫颖.荷瘤鼠乳腺癌组织的飞秒双光子荧光诊断[J].天津医科大学学报,2002,8(4):443-444,447.
作者姓名:苗绪红  李迎新  张红雨  魏赫颖
作者单位:1. 天津医科大学生物学教研室,天津,300070
2. 天津医科大学生物医学工程系,天津,300070
3. 天津大学精仪学院
摘    要:目的:检测荷瘤鼠乳腺癌组织的双光子荧光光谱。方法:乳腺癌荷瘤鼠腹腔注射血卟啉(HpD)。以飞秒激光照射小鼠的癌组织部位及周围正常组织部位。观察HpD双光子荧光光谱。结果:小鼠的癌组织部位可观察到外源性HpD双光子荧光光谱,而正常组织部位未观察到明显的双光子荧光光谱。结论:结论:飞秒激光外源性血卟啉双光子荧光诊断可作为癌症诊断的新方法。

关 键 词:乳腺癌  飞秒激光  HpD  双光子荧光  诊断  血卟啉  动物实验
文章编号:1006-8147(2002)04-0443-03

Study of HpD two - photon fluorescence of cancer tissue of TA2 stimulated by femtosecond laser
MIAO Xu-hong,LI Ying-xin,ZHANG Hong-yu,WEI He-ying.Study of HpD two - photon fluorescence of cancer tissue of TA2 stimulated by femtosecond laser[J].Journal of Tianjin Medical University,2002,8(4):443-444,447.
Authors:MIAO Xu-hong  LI Ying-xin  ZHANG Hong-yu  WEI He-ying
Institution:MIAO Xu-hong1,LI Ying-xin2,ZHANG Hong-yu2,WEI He-ying3
Abstract:Objective: To study the HpD two-photon fluorescence of cancer tissue of TA2.Methods:Femtosecond optical pulse laser stimulates cancer tissue and normal tissue of TA2 injected HpD,then to observe the spectrum of two-photo fluorescence of HpD.Results: The spectrum of two-photon fluorscence of HpD is observed in cancer tissue,but there is no such spectrum in the normal tissue.Conclusion:Oberservating the HpD two-photon fluorescence will be an new effective method in diagnosing cancer field.
Keywords:Femtosecond laser  HpD  Two-photo fluorescence  Cancer diagnosing
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