Differential gene expression between asymptomatic HBV carriers and normal adults

BACKGROUND:There are more than 100 million asymptomatic HBV carriers(ASCs)in China and they are at a high risk of developing liver disease,which creates a serious health problem.But more than 90%of normal adults clear virus from primary HBV infection,so the difference of gene expression between ASCs and normal adults determines the differential outcomes.To identify differentially expressed genes in ASCs compared to normal adults,we used suppression subtractive hybridization to compare gene expression. METHO...