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白酒对健康大鼠凝血及纤溶的影响
引用本文:魏陵博 丁书文 戎冬梅. 白酒对健康大鼠凝血及纤溶的影响[J]. 中国预防医学杂志, 2005, 6(5): 409-410
作者姓名:魏陵博 丁书文 戎冬梅
作者单位:[1]青岛市海慈医疗集团中医心内科,山东266033 [2]山东中医药大学附属医院心内科
摘    要:
目的探讨白酒对健康大鼠凝血及纤溶的影响.方法将大鼠随机分为正常对照组、阿司匹林组、白酒低、中、高剂量组,灌胃4个月后,抽静脉血查PT、FB、TT、PAI、t-PA.结果白酒高剂量组与其他组相比PT延长,差异有统计学意义,P<0.05.FB、TT;t-PA、PAI值各组间差异无统计学意义,P>0.05.结论白酒高剂量可使大鼠的PT延长,具有抗凝作用.

关 键 词:白酒  大鼠  凝血功能
收稿时间:2005-01-08
修稿时间:2005-01-08

Effects of Alcohol on Coagulation and Fibrinolysis in Healthy Rats
WEI LIng - bo , DING Shu - wen, RONG Dong - mei.. Effects of Alcohol on Coagulation and Fibrinolysis in Healthy Rats[J]. China Preventive Medicine, 2005, 6(5): 409-410
Authors:WEI LIng - bo    DING Shu - wen   RONG Dong - mei.
Affiliation:Traditional Chinese Medicine Heart Internal Medicine of HISER Medical Center of Qingdao, Qingdao 266033, China
Abstract:
Objective To investigate the effects of Liquor Wine on coagulation and fibrinolysis in rats. Methods The rats were randomly devided into five groups: the normal control group, the aspirin group, the low-dose wine group, the moderate - dose wine group and the high- dose wine group.After the rats were fed for 4 months, the blood in vein were drew to test PT, FB,TT, PAI, t - PA. Results The PT of high - dose wine group was longer than that of other groups.There were significant differences among them (P<0.05) .There were not significant differences among those groups on FB, TT, t-PA, PAI(P>0.05).Conclusion The high - dose wine make PT longer of rats, and it has anti - coagulation effect.
Keywords:PAI  t-PA
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