液基薄层细胞检测及TBS分类在宫颈癌筛查中的应用

目的 :对液基薄层细胞检测系统 Autocyte Prep L iquid based Cytology Test (L CT)及 the Bethesda sytem(TBS)细胞学分类法在宫颈癌筛查中的应用价值进行综合评价。方法 :采用液基薄层细胞检测系统检测宫颈细胞并进行 TBS细胞学分类诊断 ,将诊断意义不明的不典型鳞状细胞 (ASCUS)以上病变均列为阳性病例 ,且在阴道镜下行活检 ,将细胞学检测结果与活检结果作对比分析。结果 :液基薄层细胞检测法标本满意率 95 % ,180 0例涂片中阳性病例 76例 ,阳性率 4 .2 2 % (76 / 180 0 ) ,对 76例异常者行阴道镜下活检与组织病理学诊断总符合率 81.5 % (6 2 / 76 )。结论 :L CT技术应用于宫颈细胞涂片筛查 ,明显提高了涂片的满意率及宫颈异常细胞检出率。 TBS报告方式内容直观、易懂、具体。 L CT检查异常的病例配合阴道镜病理检查进行最后诊断 ,能及早发现宫内早期病变 ,是防治宫颈癌发生的关键

Application of liquid based cytology test and TBS cytology subdivision in the dete ction of cervical cancer

Objective:To study the value of liquid based cytology test(LCT)and Bethesda(TBS)cytology subdivision in the detection of cervical cancer.Methods:1 800 cases were detected using LCT and TBS.The samples of atyical squamous cell and more abnormal cell were positive,then compared the positive results with colposcopical biospy examination.Results:The satisfactory rate of LCT smears was 95%,76 samples were positive, the positive rate was 4.33%(76/1 800).Of these 76 cases,62 cases were agreement with the pathological examination,the rate of agreement was 81.5%(62/76).Conclusion:If combined with colposcopical and pathological examination,LCT could find out the early cervical lesions as soon as possible.The TBS cytology subdivision is more detailed,simple and direct.It is the key to prophylaxis and treatment of cervical cancer.