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高剂量表阿霉素的CHOP方案治疗非霍奇金淋巴瘤
引用本文:王志梅,陈祖聪,徐建民. 高剂量表阿霉素的CHOP方案治疗非霍奇金淋巴瘤[J]. 临床肿瘤学杂志, 2002, 7(4): 253-255
作者姓名:王志梅  陈祖聪  徐建民
作者单位:200032,上海,复旦大学附属中山医院血液科;云南省德宏州西市医院内科
摘    要:目的 :观察高剂量表阿霉素组成的CHOP方案治疗非霍奇金淋巴瘤 (NHL)的疗效及其不良反应。方法 :表阿霉素 90 5mg/m2 组成的CHOP方案治疗 30例淋巴瘤患者。结果 :完全缓解 73 3% ,部分缓解 2 6 7%。主要副反应为骨髓抑制 ,表现为白细胞下降 ,对血小板及血红蛋白的影响轻微 ;急性心脏毒性不明显 ,未见其它严重不良反应。结论 :以高剂量表阿霉素组成的CHOP方案治疗NHL疗效高、安全性好

关 键 词:非霍奇金淋巴瘤  表阿霉素  高剂量
文章编号:1009-0460(2002)04-0253-03
修稿时间:2001-06-22

Treatment of non-Hodgkin''''s lymphoma with CHOP comprising of high dose epirubicin
Wang Zhimei,Chen Zucong,Xu Jianmin. Treatment of non-Hodgkin''''s lymphoma with CHOP comprising of high dose epirubicin[J]. Chinese Clinical Oncology, 2002, 7(4): 253-255
Authors:Wang Zhimei  Chen Zucong  Xu Jianmin
Affiliation:Wang Zhimei,Chen Zucong,Xu Jianmin. Department of Hematology,The affiliated Zhong Shan Hospital of Fu Dan University,Shanghai 200032
Abstract:Objective:To investigate the efficacy and side effects of CHOP comprising of high dose epirubicin in the treatment of non Hodgkin's lymphoma. Methods:30 patients with non Hodgkin's lymphoma were treated with CHOP comprising of epirubicin 90 5 mg/m 2 body area. Results:Complete remission is 73 3%, partial remission is 26 7%. The chief side effects is myelosuppression, acute cardiotoxicity and other serious side effects are not observed. Conclusion:CHOP comprising of high dose epirubicin is safe and highly effective in the treatment of non Hodgkin's lymphoma.
Keywords:Non Hodgkin's lymphoma  Epirubicin  High dose
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