| 氯硝西泮治疗社交恐怖症 |
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| 引用本文： | 吕建周,盛民生,杨静娟. 氯硝西泮治疗社交恐怖症[J]. 中国新药与临床杂志, 1999, 18(3): 151-152 |
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| 作者姓名： | 吕建周 盛民生 杨静娟 |
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| 作者单位： | 洛阳荣康医院,河南洛阳471013 |
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| 摘 要： | 目的：观察氯硝西泮治疗社交恐怖症的疗效。方法：社交恐怖症３６例（男性１５例,女性２１例,年龄２６ａ±ｓ８ａ,病程４．０ａ±２．０ａ）采用氯硝西泮４～１０ｍｇ／ｄ,ｐｏ,疗程８ｗｋ。另外采用丙米嗪治疗同类病人３２例（男性１４例,女性１８例,年龄２５．０ａ±２．７ａ,病程３．４ａ±２．７ａ）,用量１００～３００ｍｇ／ｄ,ｐｏ,疗程８ｗｋ。结果：氯硝西泮组显效率为５６％,总有效率为８１％;丙米嗪组显效率为５０％,总有效率７５％,２组疗效差异无显著意义（Ｐ＞０．０５）,氯硝西泮组不良反应较丙米嗪组少。结论：氯硝西泮对社交恐怖症有肯定的治疗作用,近、远期疗效较好,且不良反应较少。
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| 关 键 词： | 氯硝西泮 丙米嗪 恐怖症 |
Clonazepam in treating social phobia |
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| L Jian-Zhou,SHENG Min-Sheng,YANG Jing-Juan. Clonazepam in treating social phobia[J]. Chinese Journal of New Drugs and Clinical Remedies, 1999, 18(3): 151-152 |
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| Authors: | L Jian-Zhou SHENG Min-Sheng YANG Jing-Juan |
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| Affiliation: | L(U) Jian-Zhou,SHENG Min-Sheng,YANG Jing-Juan |
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| Abstract: | AIM: To observe the efficacy of clonazepam in treating social phobia. METHODS: Thirty_six patients (M 15, F 21; age 26 a sTBZ] 8 a; course 4.0 a2.0 a) with social phobia were given clonazepam 4_10 mg/d, po , for 8 wk. Another thrity_two patients (M 14, F 18; age 24.0 a2.7 a; course 3.4 a2.7 a) were given imipramine 100_300 mg/d, po , for 8 wk. RESULTS: The excellent response rates of clonazepam group and imipramine group were 56% and 50%, the total response rates of clonazepam group and imipramine group were 81% and 75%, respectively ( P >0.05). Adverse reactions of clonazepam group were less than imipramine group. CONCLUSION: Clonazepam in treating social phobia include short_term and long_term effects is really efficacious, adverse reactions of clonazepam is mild and rare. |
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| Keywords: | clonazepam imipramine phobia disorders |
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