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联合氟哌噻吨美利曲辛治疗餐后不适综合征的疗效观察
引用本文:郭勤,沈守荣,唐五良,王芬,袁秀洪. 联合氟哌噻吨美利曲辛治疗餐后不适综合征的疗效观察[J]. 医学临床研究, 2010, 27(5): 845-847
作者姓名:郭勤  沈守荣  唐五良  王芬  袁秀洪
作者单位:中南大学湘雅三医院消化内科,湖南,长沙,410013
摘    要:
[目的]探讨联合抗抑郁药氟哌噻吨美利曲辛(黛力新)治疗餐后不适综合征的临床疗效.[方法]将84例病程〉6个月的餐后不适综合征患者,随机分为2组,对照组42例应用内科常规治疗,治疗组42例在对照组基础上加用黛力新联合治疗,治疗时间均为12周.以餐后不适综合征症状评定量表(PDSR)评定疗效,SDS抑郁自评量表诊断抑郁症.[结果]治疗12周,治疗组及对照组显效率分别为71.7%(29/42)及47.8%(20/42),治疗组SDS评分减少,差异有显著性(P〈0.05).[结论]联合抗抑郁药黛力新治疗餐后不适综合征疗效显著,是一个理想的餐后不适综合征治疗方案.

关 键 词:综合征/药物疗法  氟哌噻吨/投药和剂量  抗焦虑药/投药和剂量

Efficacy of Routine Medicine Combined with Flupentixol and Melitracen in the Treatment of Postprandial Dyspepsia Syndrome
Affiliation:GUO Qin, SHEN Shou-rong, TANG Wu-liang,et al ( Third Xiangya Hospital, Central South University, Changsha 410006, China )
Abstract:
[Objective] To explore the clinical efficacy of routine medicine combined with flupentixol and melitracen(Deanxit) in the treatment of postprandial dyspepsia syndrome (PDS) . [Methods] A total of 84 PDS patients with the course of over 6 months were randomly divided into two groups. The treatment group ( n =42) received routine medicine plus antidepressant Deanxit. The control group (n =42) was given only routine medicine. They were all treated for 12 weeks. The clinical efficacy was assessed by PDS rating scale (PDSR). SDS self-rating depression scale was used for diagnosing depression. [Results]After treatment for 12 weeks, the excellent rate in treatment group and control group was 71.7% (29/42) and 47.8% (20/42), respectively. SDS score was reduced in treatment group and there was significant difference between two groups( P 〈0.05). [Conclusion] The routine medicine combined with antidepressant Deanxit has obvious efficacy for the treatment of PDS, so it is an ideal therapeutic schedule.
Keywords:syndrome/DT  flupenthixol/AD  anti-anxiety agents/AD
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