血府逐瘀汤治疗慢性肾功能衰竭的临床观察

目的:探讨中药复方血府逐瘀汤治疗慢性肾功能衰竭的临床疗效。方法:对75例慢性肾功能衰竭患者,随机分为治疗组40例、对照组35例,两组患者在基础治疗的同时,治疗组采用血府逐瘀汤加爱西特片,对照组采用爱西特片。观察两组治疗后的总有效率及血肌酐(Scr)、内生肌酐清除率(Ccr)的变化。结果:治疗组总有效率为92.5%,对照组总有效率为71.43%,两组疗效比较有统计学意义(P<0.05);Scr的下降、Ccr的上升,治疗组优于对照组(P<0.05)。结论:中药复方血府逐瘀汤能有效地降低Scr,提高Ccr,延缓肾功能恶化。

Clinical Observation on Treatment of Chronic Renal Failure With Xuefu Zhuyu Decoction

Objective:To investigate therapeutic effect of TCM compound of Xuefu Zhuyu Decoction(XFZYD) in treating Chronic Renal Failure(CRF).Methods:seventy-five CRF patients were randomly divided into the treated group(n=40)and the control group(n=35).The treated group was treated with XFZYD and Medical charcoal.The control group was only treated with Medical charcoal.The changes of total effective rate,serum creatinine(Scr)and creatinine clearance(Ccr)in two groups were compared.Result:The total effective rate of the treating group is 92.50 percent,while the control group is 71.43 percent.The comparison of therapeutic effect in two gropus were significant(P<0.05).The decrease of Scr and increase of Ccr in the treated group was more significant than in the contol group(P<0.05).Conclusion:TCM compound of Xuefu Zhuyu Decoction has good effect in decreasing Scr and increasing Ccr and postpone the aggravation of renal function.