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| 尿素乳膏治疗手足皲裂症临床研究 | |
| 引用本文： | 赵东坤. 尿素乳膏治疗手足皲裂症临床研究[J]. 中国现代药物应用, 2009, 3(9): 7-8 |
| 作者姓名： | 赵东坤 |
| 作者单位： | 山东省淄博市中心医院,255036 |
| 摘 要： | 目的评价本院自制制剂尿素乳膏治疗手足皲裂症的疗效和安全性。方法采用随机双盲、安慰剂对照研究，试验组和对照组均为局部用药，2次／d，疗程4周。结果手足皲裂患者26例，包括试验组和对照组各13例。治疗4周后，试验组的总有效率为100％，而对照组的总有效率为61．6％。两组之间的有效率比较，具有统计学意义（P〈0．01）。试验组有1例发生不良事件。结论尿素乳膏治疗手足皲裂症具有很高的疗效，且安全性和耐受性良好，使用方便。 |
| 关 键 词： | 手足皲裂症 尿素乳膏 临床研究 疗效 |
A clinical trial of urea acid compound ointment for the treatment of rhagadia manus et pedis |
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| ZHAO Dong-kun. A clinical trial of urea acid compound ointment for the treatment of rhagadia manus et pedis[J]. Chinese Journal of Modern Drug Application, 2009, 3(9): 7-8 | |
| Authors: | ZHAO Dong-kun |
| Affiliation: | ZHAO Dong-kun.( Central Hospitalof ZiBo ; ZiBo , Shandong ,255036 , China ) |
| Abstract: | Objective To evaluate the efficacy and safety of urea acid compound ointment for the treatment of rhagadia manus et pedis. Methods The trail was performed in randomized double-blind and placebo control method. All the subjects were administratd with drugs twice a day for four weeks. Results The total number of all the subjects was 26; including 13 subjects in trial group and 13 subjects in control group. The total improved rates were 100% in trail group after four-week therapy; while in control group; were 61.6%. The improved rates between two groups had statistic differences （ P 〈 0. 01 ）. One case of adverse event occured in trail group. Conclusion The urea acid compound ointment has good efficacy; safety and tolerability in treatment of rhagadia manus et pedis ; and can be used conveniently. |
| Keywords: | Rhagadia manus et pedis Urea＆lactic acid compound ointment |
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