| 人参皂苷Rg1对急性心肌缺血豚鼠心电图的影响 |
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| 引用本文： | 来方远,潘永明,艾秀锋,贾临超,朱科燕,杨玉伟,陈民利.人参皂苷Rg1对急性心肌缺血豚鼠心电图的影响[J].中华中医药学刊,2011(11):2529-2533. |
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| 作者姓名： | 来方远 潘永明 艾秀锋 贾临超 朱科燕 杨玉伟 陈民利 |
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| 作者单位： | 浙江中医药大学第二临床医学院;浙江中医药大学动物实验研究中心; |
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| 基金项目： | 浙江省大学生科技创新项目(2010R410004); 浙江省卫生高层次创新人才培养工程资助项目 |
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| 摘 要： | 目的:探讨人参皂苷Rg1的抗缺血作用。方法:建立垂体后叶素致豚鼠急性心肌缺血模型,采用无创生理信号处理遥测系统测定人参皂苷Rg1对豚鼠II导联心电图变化的影响。结果:人参皂苷Rg1对垂体后叶素诱发豚鼠心电图T波、ST段的抬高具有明显的降低作用(P<0.05,P<0.01),并能抵抗心率的减慢和PR间期、QRS波群、QT间期的延长。结论:人参皂苷Rg1具有显著对抗垂体后叶素致豚鼠急性心肌缺血的作用。
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| 关 键 词： | 人参皂苷Rg1 心肌缺血 心电图 豚鼠 |
The Effect of Ginsenoside Rg1 on ECG of Acute Myocardial Ischemia in Guinea Pigs |
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| LAI Fang-yuan,PAN Yong-ming,AI Xiu-feng,JIA Lin-chao,ZHU Ke-yan,YANG Yu-wei,CHEN Min-li.The Effect of Ginsenoside Rg1 on ECG of Acute Myocardial Ischemia in Guinea Pigs[J].Chinese Archives of Traditional Chinese Medicine,2011(11):2529-2533. |
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| Authors: | LAI Fang-yuan PAN Yong-ming AI Xiu-feng JIA Lin-chao ZHU Ke-yan YANG Yu-wei CHEN Min-li |
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| Institution: | LAI Fang-yuan1,PAN Yong-ming2,AI Xiu-feng2,JIA Lin-chao2,ZHU Ke-yan2,YANG Yu-wei2,CHEN Min-li2(1.Second Affilated Hospital of Zhejiang Chinese Medical University of TCM,Hangzhou 310053,Zhejiang,China,2.Zhejiang Chinese Medical University,China) |
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| Abstract: | Objective: To observe the protective effect of Ginsenoside Rg1 on acute myocardial ischemia.Methods: Acute myocardial ischemia Guinea pig model was induced by pituitrin,the effect of Ginsenoside Rg1 on ECG in acute myocardial ischemia Guinea pigs was observed by Non-Invasively Telemetry.Results: Ginsenoside Rg1 could reduce the heights of ST segment and T wave which caused by injecting pituitrin(P<0.05,P<0.01),and resist the reduce of heart rate and prolong of PR interval,QRS wave group and QT interval.Conc... |
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| Keywords: | Ginsenoside Rg1 Myocardial ischemia ECG Guinea pig |
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