Synthesis and Pharmacological Activity of N-[β-(para-substituted benzoyl)ethyl]isoleucine and -Methionine |
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Authors: | A. G. Agababyan A. Y. Isakhanyan O. A. Papoyan A. E. Tumadzhyan A. S. Balasanyan G. A. Gevorgyan |
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Affiliation: | (1) Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of Armenia, Yerevan, Armenia |
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Abstract: | A series of N-[β-(p-substituted benzoyl)ethyl]-isoleucine and -methionine derivatives have been synthesized via the alkylation of amino acids with p-substituted β-diethylaminopropiophenone hydrochlorides. Some of the synthesized compounds possess significant antiinflammatory activity. __________ Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 39, No. 7, pp. 26 – 27, July, 2005. |
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