| 贞冰口溃宁片质量标准的建立 |
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| 引用本文： | 顾成刚,胡俊杰,郑国华,吴宁.贞冰口溃宁片质量标准的建立[J].中国药师,2014(3):397-400. |
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| 作者姓名： | 顾成刚 胡俊杰 郑国华 吴宁 |
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| 作者单位： | 湖北中医药大学药学院 武汉 430065；;湖北中医药大学药学院 武汉 430065；;湖北中医药大学药学院 武汉 430065；;武汉药谷科技开发有限公司 |
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| 摘 要： | 目的：建立贞冰口溃宁片质量标准.方法：采用TLC法对处方中黄连、赤芍、栀子、冰片进行定性鉴别;采用HPLC法测定齐墩果酸和熊果酸含量.结果：在TLC图谱中可检出黄连等药材的特征斑点;测得齐墩果酸和熊果酸平均回收率分别为98.3%、99.2%（n=6）.结论：所采用方法准确、可靠,重复性良好,能用于控制该制剂的质量.
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| 关 键 词： | 贞冰口溃宁片 薄层色谱法 高效液相色谱法 齐墩果酸 熊果酸 |
| 收稿时间： | 2013/10/12 0:00:00 |
| 修稿时间： | 2013/12/14 0:00:00 |
Study on Quality Standard of Zhenbing Koukuining Tablets |
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| Gu Chenggang,Hu Junjie,Zheng Guohua and Wu Ning.Study on Quality Standard of Zhenbing Koukuining Tablets[J].China Pharmacist,2014(3):397-400. |
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| Authors: | Gu Chenggang Hu Junjie Zheng Guohua and Wu Ning |
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| Institution: | 1. College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China;2. Wuhan Yaogu Science and Technology Development Co. , Ltd. ) |
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| Abstract: | Objective： To establish the quality control method for Zhenbing Koukuining tablets. Methods： Coptidis rhizoma, Pae- oniae radix rubra, Gardeniae fructus and Borneolum syntheticum were detected by TLC, and the contents of oleanolic acid and ursolic acid were determined by HPLC. Results ： The medicinal herbs could be identified by TLC. The average recovery of oleanolie acid and ursolic acid was 98.3% and 99.2% （n = 6）, respectively. Conclusion： The method i~ accurate, reliable and repeatable, which can be used in the quality control of the preparation. |
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| Keywords: | Zhenbing Koukuining tablets TLC HPLC Oleanolic acid Ursolic acid |
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