金属有机骨架作为药物载体的研究进展 |
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引用本文: | 董玉晶,李永吉,林瀚,白欣玉.金属有机骨架作为药物载体的研究进展[J].黑龙江医药,2014,27(5):1032-1034. |
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作者姓名: | 董玉晶 李永吉 林瀚 白欣玉 |
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作者单位: | 1. 黑龙江中医药大学药学院 2. 黑龙江中医药大学 黑龙江哈尔滨150040 |
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基金项目: | 国家自然科学基金面上项目;项目,教育部博士点基金项目,项目 |
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摘 要: | 目的:综述金属有机骨架作为几种药物载体的研究进展。方法:根据近年来国内外文献资料,对金属有机骨架储存和释放不同药物及其细胞毒性的研究进行归纳、分析和总结。结论:金属有机骨架具有载药量高、缓控释效果好和与体内的生物相容性良好等优点。作为药物载体具有良好的应用前景。
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关 键 词: | 金属有机骨架 药物 载体 |
Research Development of Metal-Organic Frameworks as Drug Carriers |
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Institution: | Dong Yujing , et al (Pharmacy College, Heilongjiang University of Traditional Chinese Medicine (150001)) |
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Abstract: | Objective: To state the research development of Metal-Organic frameworks as drug carriers. Methods: According to the literature at home and abroad in recent yea~, analyze and summarize the research of Metal-Organic Frameworks for store and release of different drugs , and its cytotoxicity. Conclusion: Metal-Organic Frameworks have emerged as a promising platform for drug delivery, owing to the advantages of their high drug loadings, slow-release effect and biodegradability etc. |
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Keywords: | Metal-Organic Frameworks Drug Carriers |
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