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Physiological and behavioral effects of prior aversive stimulation (preshock) in the rat
Authors:S Levine  J Madden  R L Conner  J R Moskal  D C Anderson
Institution:Department of Psychiatry, Stanford University School of Medicine, Stanford, California 94305 USA;Department of Psychology, Bowling Green State University, Bowling Green, Ohio 43403 USA;Departments of Chemistry and Psychology, University of Notre Dame, Notre Dame, Indiana 46556 USA
Abstract:Physiological and behavioral measures were assessed in rats that had been previously exposed to unsignaled inescapable intense shock (preshock). Animals subjected to such prior aversive stimulation exhibited greater adrenocortical steroid response compared to nonpreshocked controls when subsequently tested in the open field. An increment in defecation was also observed, with ambulation and rearing behavior being markedly inhibited in the preshocked rat during these sessions.
Keywords:Preshock  Punishment  Open field  Novelty  Emotionality  Activity  Defecation  Plasma corticosterone
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