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Hypotetraploidy in erythroleukemia
Authors:E C Douglass  D L Freeman
Affiliation:Department of Pediatrics, University of South Florida College of Medicine, Tampa, Florida USA
Abstract:
Cytogenetic study of a case of erythroleukemia in a 9-year-old white male showed a modal number of 72 with tetraploidy of several chromosomes and duplication of markers. The disease had a very rapid initial response to therapy. The uniqueness of this karyotype and its relationship to previously reported cytogenetic studies on erythroleukemia are discussed.
Keywords:Address requests for reprints to Dr. Edwin C. Douglass   St. Jude Children's Research Hospital   332 North Lauderdale   P.O. Box 318   Memphis   Tennessee 38101.
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