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| 基质金属蛋白酶-9与体外循环肺损伤 | |
| 引用本文： | 申翼,张宝仁,景华. 基质金属蛋白酶-9与体外循环肺损伤[J]. 医学研究生学报, 2004, 17(10): 925-928 |
| 作者姓名： | 申翼 张宝仁 景华 |
| 作者单位： | 南京军区南京总医院,第二军医大学南京临床学院,心胸外科,江苏南京,210002 |
| 摘 要： | 肺泡毛细血管基膜损伤是体外循环(CPB)术后肺损伤发生发展的主要病理过程，基质金属蛋白M-9(MMP-9)可能通过降解细胞外基质、调节细胞因子而参与CPB所致损伤的发生，研究MMP-9在CPB肺损伤中的作用机制，对于防治CPB术后肺损伤的发生发展具有重要意义。 |
| 关 键 词： | 基质金属蛋白酶-9 体外循环 肺损伤 |
| 文章编号： | 1008-8199(2004)10-0925-04 |
| 修稿时间： | 2003-12-13 |
Current progress of matrix metalloproteinase in acute lung injury following cardiopulmonary bypass |
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| SHEN Yi reviewing,ZHANG Bao-ren,JING Hua checking. Current progress of matrix metalloproteinase in acute lung injury following cardiopulmonary bypass[J]. Bulletin of Medical Postgraduate, 2004, 17(10): 925-928 | |
| Authors: | SHEN Yi reviewing ZHANG Bao-ren JING Hua checking |
| Abstract: | Degradation of basement membrane of pulmonary capillaries was the main pathological feature of lung injury following cardiopulmonary bypass (CPB). Matrix metalloproteinases-9 (MMP-9) contributed to the development of lung injury following CPB via degredating extracellular matrix and regulating cytokines. So, understanding the effects of MMP-9in the lung injury following CPB may be helpful to prevent and treat the complication mentioned above. |
| Keywords: | Matrix metalloproteinase Cardiopulmonary bypass Lung injury |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |