快速免疫色谱测定法在骨关节结核诊断及鉴别诊断中的价值

目的探讨快速免疫色谱法对活动性骨关节结核的诊断价值。方法采用ＩＣＴ快速免疫色谱法检测７５例活动性骨关节结核、６９例以肿瘤为主的骨病患者及７２名正常人血清中的抗体。结果骨关节结核组阳性率为８０％，其中脊柱结核阳性率为９０％，脊柱以外的关节结核阳性率为６１％，合并其它部位结核阳性率为７６％；骨病组３例阳性，正常组２例阳性，假阳性率分别为４％和３％。结论ＩＣＴ快速免疫色谱法是骨关节结核诊断和鉴别诊断的一项有用的辅助手段

Clinical value of a rapid immunochromatographic assay in diagnosis and differential diagnosis of bone and joint tuberculosis

Objective To evaluate the clinical value of a rapid immunochromatographic assay in diagnosis and differential diagnosis of bone and joint tuberculosis. Method Antibodies in sera from 75 patients with active bone and joint tuberculosis, 69 patients with non tuberculous bone and joint diseases and 72 healthy individuals were detected by the rapid immunochromatographic assay using ICT TB kit. Result The positive rate was found to be 80% in the patients with active bone and joint tuberculosis, while 90% in the group with spinal tuberculosis, 53% in the extra spinal articular tuberculosis. The false positive rates were 4% and 3% respectively in those with other bone and joint diseases and healthy individuals. Conclusion The assay is a rapid, sensitive and specific supplementary tool for the diagnosis of the bone and joint tuberculosis.