| CGRP1受体在大鼠牙齿及牙周组织中的表达 |
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| 引用本文： | 赵昱辉,段银钟,孙应明. CGRP1受体在大鼠牙齿及牙周组织中的表达[J]. 临床口腔医学杂志, 2004, 20(11): 643-645 |
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| 作者姓名： | 赵昱辉 段银钟 孙应明 |
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| 作者单位： | 第四军医大学口腔医学院正畸科,陕西,西安,710032;四川大学华西口腔医学院 |
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| 基金项目： | 国家自然科学基金资助项目 (30 2 0 0 32 0 ) |
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| 摘 要： | 目的 :研究大鼠牙体、牙周组织中神经肽CGRP1受体的存在及其结合位点。方法 :利用原位杂交方法对大鼠牙齿及牙周组织切片进行染色 ,在显微镜下观察CGRP1受体的定位。结果 :CGRP1受体主要存在于大鼠牙髓及牙周组织的较大血管内皮细胞 ,未在硬组织内发现CGRP1受体。结论 :CGRP1受体在口腔组织中主要分布于较大血管 ,CGRP通过CGRP1受体对大血管起作用 ,调节口腔血流传导信号。
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| 关 键 词： | 降钙素基因相关肽 受体 牙髓 血管 |
| 文章编号： | 1003-1634(2004)11-0643-03 |
Expression of CGRP1 receptor in rat dental hard tissues and in peridental tissue |
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| ZHAO Yu-hui,DUAN Yin-zhong,SUN Ying-ming.Stomatological Collog e,The Fourth Military Medical University,Xi'an ,China [. Expression of CGRP1 receptor in rat dental hard tissues and in peridental tissue[J]. Journal of Clinical Stomatology, 2004, 20(11): 643-645 |
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| Authors: | ZHAO Yu-hui DUAN Yin-zhong SUN Ying-ming.Stomatological Collog e The Fourth Military Medical University Xi'an China [ |
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| Affiliation: | ZHAO Yu-hui,DUAN Yin-zhong,SUN Ying-ming.Stomatological Collog e,The Fourth Military Medical University,Xi'an 710032,China [ |
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| Abstract: | Objective:To investigate the existence an d localization of CGRP1 re ceptor in rat dental hard tissues and in peridental tissue.Method: Colorate th e slice of the rat dental hard tissues and peridental tissue by the method of hy bridization in situ. Observe the location of CGRP1 receptor by microscope.Resul t: The CGRP1 receptors were distributed in the endothelial cells of the larger blood vessel in peridental tissue,did not found CGRP1 receptors in dental hard tissues.Conclusion: The CGRP1 receptor were distributed in the l arger blood ve ssel. Through CGRP1 receptor,CGRP have effects on larger blood vessel,regulate b lood stream and transfer signal. [ |
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| Keywords: | calcitonin gene-related peptide receptor dental pulp b lood vessel |
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