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双歧杆菌对小鼠体液免疫功能的影响
引用本文:梁庆红,王倩,张琳,张亚超,王沛,周志广. 双歧杆菌对小鼠体液免疫功能的影响[J]. 承德医学院学报, 2004, 21(2): 100-101
作者姓名:梁庆红  王倩  张琳  张亚超  王沛  周志广
作者单位:河北医科大学第三医院,河北,石家庄,050000;中国人民解放军白求恩军医学院;河北迁安市人民医院
摘    要:
目的:探讨双歧杆菌减少对小鼠体液免疫功能的影响.方法:抗生素脱污染造成肠道双歧杆菌数量减少,溶血空斑实验测定抗体生成细胞的数量并测量的重量.结果:实验组小鼠肠道内双歧杆菌数量明显低于对照组(P<0.01);脾细胞悬液的溶血空斑细胞数量及脾脏的重量均较对照组明显减少(P<0.01);双歧杆菌数量与溶血空斑细胞数和脾脏重量呈显著正相关.结论:双歧杆菌减少可降低机体体液免疫功能,双歧杆菌对机体体液免疫功能的调节发挥着重要的作用.

关 键 词:双歧杆菌  体液免疫功能  菌群失调
文章编号:1004-6879(2004)02-0100-02
修稿时间:2004-01-09

INFLUENCE OF BIFIDOBACTERIUM ON MURINE HUMORAL IMMUNE FUNCTION
LIANG Qing hong,WANG Qian,ZHANG Lin,et al. INFLUENCE OF BIFIDOBACTERIUM ON MURINE HUMORAL IMMUNE FUNCTION[J]. Journal of Chengde Medical College, 2004, 21(2): 100-101
Authors:LIANG Qing hong  WANG Qian  ZHANG Lin  et al
Abstract:
Objective:To explore the influence of Bifidobacterium on murine humoral immune function.Methods:Bifidobacterium is decreased by antibiotics.Results:1.In the test group,the number of Bifidobacterium is obviously smaller than that in contrast group (P<0.01).2.The number of PFC cell,the weight of the spleen in the test group have obviously decreased when compared with that in the control group (P<0.01).3.Analysis of the correlations shows that there are marked positive correlations between Bifidobacteria and each immune index.Conclusion:The results suggest that the smaller number of Bifidobacteria may decrease the humoral immune function.
Keywords:Bifidobacteria  humoral immune function  dysbacteriosis
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