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Syk/Src-targeted anti-inflammatory activity of Codariocalyx motorius ethanolic extract |
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| Authors: | Eunji Kim Kee Dong Yoon Woo-Shin Lee Woo Seok Yang Shi Hyoung Kim Nak Yoon Sung Kwang-Soo Baek Yong Kim Khin Myo Htwe Young-Dong Kim Sungyoul Hong Jong-Hoon Kim Jae Youl Cho |
| Institution: | 1. Department of Genetic Engineering, Sungkyunkwan University, Suwon 440-746, Republic of Korea;2. College of Pharmacy, The Catholic University of Korea, Bucheon 420-743, Republic of Korea;3. Department of Forest Sciences, Seoul National University, Seoul 151-921, Republic of Korea;4. Popa Mountain Park, Forest Department, Kyaukpadaung Township, Mandalay Division, Myanmar;5. Department of Life Science, Hallym University, Chuncheon 200-702, Republic of Korea;6. Department of Veterinary Physiology, College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Jeonju 561-756, Republic of Korea |
| Abstract: | |
| Keywords: | Cm-EE ethanolic extract of Codariocalyx motorius PGE2 prostaglandin E2 NO nitric oxide COX cyclooxygenase iNOS inducible NO synthase (TNF)-α tumour necrosis factor TLR toll-like receptors (TLR) NF-κB nuclear factor-κB AP-1 activator protein-1 AKT protein kinase B AP-1 activator protein-1 IKK IκBα kinase Syk spleen tyrosine kinase EIA enzyme immunoassay MTT (3-4 5-dimethylthiazol-2-yl)-2 5-diphenyltetrazolium bromide LPS lipopolysaccharide |
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