老年男性2型糖尿病患者骨密度变化的分析

目的:探讨老年男性2型糖尿病患者骨密度的变化情况.方法:应用双能X线骨密度测定法测定52例老年男性2型糖尿病患者腰椎和股骨颈的骨密度,同时检测身高,体重,血钙、磷、碱性磷酸酶,24 h尿钙,计算体质指数,并与46例同龄正常健康老年男性进行比较.结果:老年男性2型糖尿病患者骨质疏松症的患病率为11.5%,正常对照组骨质疏松的患病率为3.8%.两组间体质指数,血钙、磷及碱性磷酸酶无明显差异,但糖尿病组24 h尿钙高于正常对照组,差异具有显著性(P＜0.01).结论:老年男性2型糖尿病患者的骨质疏松患病率较正常男性明显增高,是2型糖尿病的常见并发症.

Analysis of bone mineral density change in type 2 diabetic elderly men

Objective:To investigate the changes in bone mineral density(BMD)in elderly men with type 2 diabetes.Methods:BMD of the proximal femur and the anteroposterior spine was determined using dual-energy X-ray absorptiometry(DEXA),and body weight,height,blood calcium,phosphorus,alkaline phosphatase,urine calcium of 24 hours were also determined in 52 men with type 2 diabetes.The same determinations were done in 46 age-matched healthy subjects.Results:The incidence of osteoporosis in elderly men with type 2 diabetes and age-matched healthy subjects was respectively 11.5% and 3.8%.No significant difference was found in blood calcium,phosphorus and alkaline phosphatase contents between two groups.In diabetic patients,24-hour urine calcium was higher compared with the normal control(P<0.01).Conclusion:The incidence of osteoporosis in elderly men with type 2 diabetes was higher,comparing with age-matched healthy subjects.Osteoporosis is a frequent complication of type 2 diabetes.