妥塞敏用于人工流产术止血的初步观察

目的　探讨妥塞敏用于早孕妇女行人工流产负压吸引术的止血效果。方法　 12 0例早孕妇女分为妥塞敏组和对照组。每组 6 0例 ,对两组妇女按妇科检查及B超测定判断孕周大小进行配对。两组妇女年龄、停经天数、孕次、宫腔大小、血红蛋白及血小板计数比较 ,差异无显著性 (P>0 0 5 ) ,具有可比性。妥塞敏组妇女在负压吸引术前 30min静脉推注妥塞敏 1g +5 %葡萄糖 2 0ml,5min推注完毕。对照组妇女在负压吸引术前 30min静脉推注 5 %葡萄糖 2 0ml,5min推注完毕。观察两组妇女的术中、术后 30min出血量及副反应。结果　 (1)妥塞敏组出血量 (5 1 6± 17 2 )ml,对照组出血量 (6 3 3± 17 1)ml,两组比较 ,差异有显著性 (P <0 0 5 )。 (2 )妥塞敏组妇女在用药过程中有 18例 (30 0 % )出现轻度恶心 ,8例 (13 0 % )轻度头晕。对照组仅 1例有轻度恶心 ,余无副反应 ,两组妇女均未做任何处理自行好转。结论　妥塞敏用于早孕妇女负压吸引术 ,有较好的止血效果 ,术中及术后出血量均明显减少 ,无严重不良副反应 ,有利于患者的恢复

Decreasing bleeding effect of transamin on the induced abortion

OBJECTIVE: To confirm the decreasing bleeding effect of transamin on the induced abortion for the early pregnancy with more than two months. METHODS: A total of 120 women are divided into two groups (60 pairs) based on the pelvic examination and the size of embryo measured by B ultrasound. Those women in the treated group (n = 60) were administed Transamin 1 g/20 ml (iv for 5 minutes) 30 minutes before operation; control group (n = 60) were given 5% glucose and saline 20 ml (iv for 5 minutes) 30 minutes before operation. RESULTS: There wasn't any singnificant difference (P > 0.05) between the two groups in the patient's age, pregnancy age, parities, the cavity volume of uterine, hemoglobin and blood platelet count. The bleeding volume was (51.6 +/- 17.2) ml for the treated group and (63.3 +/- 17.1) ml for the control group (P < 0.05). CONCLUSIONS: Transamin has effective hemostasis during the induced abortion for the early pregnancy with > 2 months. It could decrease the volume of bleeding during the operation and benefit for patients recovering.