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Hot melt extrusion as an approach to improve solubility,permeability and oral absorption of a psychoactive natural product,piperine
Authors:Eman A. Ashour  Soumyajit Majumdar  Abdulla Alsheteli  Sultan Alshehri  Bader Alsulays  Xin Feng  Andreas Gryczke  Karl Kolter  Nigel Langley  Michael A. Repka
Affiliation:1. Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University, MS, USA;2. Pii Center for Pharmaceutical Technology, The University of Mississippi, University, MS, USA;3. Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, AlKharj, Saudi Arabia;4. Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;5. Global Development and Technical Marketing, BASF SE, Ludwigshafen, 67056, Germany;6. R&D Product Management Excipients, BASF SE, Ludwigshafen, Germany;7. BASF Corporation, Tarrytown, NY, USA
Abstract:
Keywords:hot melt extrusion  permeability  piperine  solubility
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