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Timing of vitrectomy for active proliferative diabetic retinopathy
Authors:R C Ramsay  W H Knobloch  H L Cantrill
Affiliation:1. Associated Retinal Consultants, PC, William Beaumont Hospital, Royal Oak, Michigan;2. USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California;3. Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts;4. William Beaumont School of Medicine, Oakland University, Rochester, Michigan;5. Department of Ophthalmology, Srinakharinwirot University, Bangkok, Thailand;6. Department of Bioengineering, University of Washington, Seattle, Washington;7. Department of Ophthalmology, Shiley Eye Institute and Jacobs Retina Center, University of California, San Diego, La Jolla, California;1. Cornea Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland;2. School of Public Health, Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland;1. Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland;2. Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland;3. Unit on Neuron-Glia Interactions in Retinal Disease, National Eye Institute, National Institutes of Health, Bethesda, Maryland;4. Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland;1. Research Institute, William Beaumont Hospital, Royal Oak, Michigan;2. Eye Research Institute, Oakland University, Rochester, Michigan;3. Associated Retinal Consultants, William Beaumont Hospital, Royal Oak, Michigan;1. School of Materials Science and Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China;2. Key Laboratory of Transparent and Opto-functional Advanced Inorganic Materials, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050, China;3. Institute of Electrophysics, Ural Branch of Russian Academy of Sciences, 106 Amundsena Street, Ekaterinburg 620016, Russia;4. School of Materials Science and Engineering, Qiqihar University, 42 Wenhua Street, Qiqihar 161006, China
Abstract:
Eyes with active proliferative diabetic retinopathy with dense sub-hyaloid hemorrhage and significant visual loss represent an appropriate indication for prompt vitrectomy. Twenty-six such eyes in 22 patients were operated. The results are compared to 49 diabetic eyes undergoing vitrectomy for other complications of diabetic retinopathy. The results demonstrated both an improved anatomic success rate (85% compared to 73%) and a higher rate of reading visual function (54% compared to 18%) in the early vitrectomy group, substantiating the study hypothesis.
Keywords:diabetic retinopathy  vitrectomy
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