胃镜结扎及硬化剂注射治疗食管静脉曲张的临床应用

经胃镜下结扎（EVL）后附加硬化剂注射（EIS）联合治疗食管静脉曲张患者106例，101例一个月内无出血，止血率为95．3％。经过1—2次胃镜结扎治疗后再用硬化剂治疗，88例食管静脉曲张完全消失，消失率达83．0％，余18例（17％）静脉曲张明显缩小。结果提示，采用EVL和EIS联合治疗重庆食管静脉曲张与单纯使用EVL或EIS治疗的止血效果和食管静脉曲张消失率两种方法相比有显著的差异（分别为P＜0．01和P＜0．05）。它具有方法简单、安全、能有效地控制急性出血及手术后再出血，降低死亡率，使肝功能差的患者度过出血期，为择期手术创造条件。

COMBINATION THERAPY OF ENDOSCOPIC VARICEAL LIGATION WITH ENDOSCOPIC INJECTION SCLEROSANT IN TREATING ESOPHAGEAL VARICES

The combination therapy of endoscopic variceal ligation (EVL) with endoscopic injection sclerosant (EIS) wasused to treat 1O6 cases of esophageal varices. In the month following treatment, rebleeding did not occur in 101 case5(95. 3 % ). With EIS and after one or two sessions of EVL, the varices disappeared in 88 cases (83 % ), and thcvarices shrunk significantly in 18 cases (17 % ). Our study suggests that combination therapy is more effective thanusing EIS or EVL alone in treating esophagea1 varices (P < 0. 01, P < 0. 05 ). Combination therapy provides a sim-ple, safe and effective way to control acute variceal bleeding and rebleeding after surgery, which ultimately decrease5the mortality rate associated with variceal b1eeding. In addition, combination therapy helps patients improve their liv-er functions, and makes it possib1e to perform selective surgery.