2012年靖江市恙虫病危险因素的病例对照研究

目的探讨靖江市人群恙虫病感染发病的危险因素。方法采用个体匹配,按1∶2比例选择40例病例、80例对照,以入户面访方式,采用统一设计的病例对照调查表进行问卷调查,并采用单因素和多因素条件logistic回归分析对数据进行分析。结果单因素分析结果显示,以病例发病时间为参照,发病前3周,接触柴禾、曾参加田间劳动、水稻田劳动、屋内堆放农作物或秸杆、住房邻近草地等因素两组暴露率差异有统计学意义(P值均0.05);多因素分析结果显示,屋内堆放农作物或秸杆、曾参加田间劳动,病例组与对照组暴露率差异有统计学意义,其OR值(95%CI)分别为8.88(2.46~32.07)、4.12(1.23~13.81)。结论屋内堆放农作物或秸杆、曾参加田间劳动是恙虫病发病危险因素。

A case-control study of risk factors associated with scrub typhus in Jingjiang City, 2012

Objective To explore the risk factors of scrub typhus in Jingjiang City. Methods Case-control study was used with the ratio of 1 to 2,40 patients diagnosed scrub typhus were selected as cases and healthy residents matched for age and neighborhood as controls. In-home face to face interview was conducted with unified design survey questionnaire~ data was ana- lyzed by using univariable and multivariable conditional logistic regression. Results The time of onset cases as the reference, the univariate analysis showed that before 3 weeks of onset cases, exposed firewood, labor working in field and rice field, stac- king crops or straw in homes and homes located nearby bushes were risk factors associated with exposure rate between cases and controls with meaningful statistical differences （P〈~O. 05）~ multivariate analysis showed that stacking crops or straw in homes and labor working in field were risk factors with significant statistical differences（ OR = 8.88,95 % CI= 2.46--32.07,4. 12= 1.23- 13.81）. Conclusion Stacking crops or straw in homes and working in the rice fields are risk factors of scrub typhus in Jingjiang City.