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| 小鼠小肠移植模型制作的手术技术 | |
| 引用本文： | 罗宇东,逯宁,刘彤,王军,朱理玮,王鹏志. 小鼠小肠移植模型制作的手术技术[J]. 中华器官移植杂志, 2001, 22(5): 262-263 |
| 作者姓名： | 罗宇东 逯宁 刘彤 王军 朱理玮 王鹏志 |
| 作者单位： | 天津医科大学总医院普外科 |
| 摘 要： | 目的：为研究小肠移植排斥反应提供良好的动物实验模型，方法：选用BALB／c小鼠进行同种异体异位节段性小肠移植。结果：在施行的210次手术中，模型稳定后的108次小肠移植的手术成功率为74．07％。结论：精细的显微外科手术技术是减少出血，防止血管吻合口并发症和提高手术成功率的保证，掌握麻醉的深浅度，合理的补液以及加强围手术期的管理也不容忽视。 |
| 关 键 词： | 小肠移植 小鼠 动物模型 制作 手术方法 实验研究 |
Surgical procedures for the development of small bowel transplantation model in mice |
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| LUO Yudong,LU Ning,LIU Tong,et al.. Surgical procedures for the development of small bowel transplantation model in mice[J]. Chinese Journal of Organ Transplantation, 2001, 22(5): 262-263 | |
| Authors: | LUO Yudong LU Ning LIU Tong et al. |
| Affiliation: | LUO Yudong,LU Ning,LIU Tong,et al. Department of Surgery,General Hospital,Tianjin Medical University,Tianjin 300052,China |
| Abstract: | Objective To investigate the surgical procedures for the development of small bowel transplantation (SBT) model in mice in order to study the rejection of SBT. Method Segmental heterotopic SBT was performed on male BALB/c mice. Result In the 210 cases receiving SBT, the successful rate of 108 cases undergoing SBT after the model stabilized was 74.07%. Conclusions Skillfully microsurgical procedures were the most important to avoid from hemorrhage during operation, protect the complications of angioanastomosis and increase the operative successful rate. And suitable anesthesia degree, adequate transfusion of crystal liquid and excellent perioperative care were also important. |
| Keywords: | Intestine small Transplantation Mice |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |