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司帕沙星治疗肺结核的临床研究
引用本文:白锡山,廉娟雯. 司帕沙星治疗肺结核的临床研究[J]. 临床肺科杂志, 2006, 11(6): 749-750
作者姓名:白锡山  廉娟雯
作者单位:710061,西安市胸科医院、结核病胸部肿瘤医院;710061,西安市胸科医院、结核病胸部肿瘤医院
摘    要:目的评价司帕沙星治疗肺结核的疗效。方法117例初治菌阳肺结核,随机分为治疗组(2HRSP/4HR、60例)和对照组(2HRZ/4HR、57例)进行短程化疗。结果治疗组和对照组2个月痰菌阴转率分别为95.0%和82.4%;满疗程痰菌阴转率分别为98.3%和98.0%。胸部X线所见,治疗组和对照组病灶吸收率分别为98.3%和96.5%,空洞闭合率两组分别为74.2%和51.6%。治疗组和对照组不良反应发生率分别为12.5%和9.8%。结论司帕沙星是一种新的、有效的、安全的抗结核药物。

关 键 词:结核    药物疗法  司帕沙星
收稿时间:2006-06-06
修稿时间:2006-06-06

Effect of sparfloxacin in treating pulmonary tuberculosis
BAI Xishan,LIAN Juanwen. Effect of sparfloxacin in treating pulmonary tuberculosis[J]. Journal of Clinical Pulmonary Medicine, 2006, 11(6): 749-750
Authors:BAI Xishan  LIAN Juanwen
Affiliation:Xian Tuberculosis and Thoracic Tumar Hospital, Xian 710061 ,China
Abstract:Objective To assess antituberculosis efficacy of sparfloxacin.Methods 117 new smear positive pulmonary tuberculosis patients were randomly allocated into treatment group(60 cases,receiving 2HRZSP/4HR regimen) and Controls(57cases,2HRZ/4HR).Results The suptum negative conversion rates at two month in treatment group and the controls were 95.0% and 82.4% resectively,and the end of chemotheraphy 98.3%and 98.0%.Chest radiography showed remarkable improvenend.Conclusion Sparfloxacin is a effective and safety medicine which can cure pULmonary tuberculosis.
Keywords:tuberculosis sparfloxacin
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