Short team implantation studies of periodontal dressings

A modified implantation technique was used to study the early tissue reactions to three periodontal dressings (Coe-pak, Peripac, and Wondrpak). The dressings were placed in contact with an intact non-epithelialized tissue surface for 15 minutes and 3 days. The tissue reactions were assessed by histochemical and histological techniques. After 15 minutes of tissue-material contact, the most severe tissue reactions were caused by Wondrpak. When the contact period was increased to 3 days, Peripac generally showed a more severe tissue response than Wondrpak. At both contact periods Coe-pak had caused the mildest reactions.