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血清白细胞介素-6、8在异位妊娠早期诊断中的价值探讨
引用本文:杨丽娟,王永珍,张玮,戴黎华,张达言. 血清白细胞介素-6、8在异位妊娠早期诊断中的价值探讨[J]. 江西医药, 2009, 44(6): 553-555
作者姓名:杨丽娟  王永珍  张玮  戴黎华  张达言
作者单位:江西省南昌市第三医院,南昌,330009;江西省南昌市第三医院,南昌,330009;江西省南昌市第三医院,南昌,330009;江西省南昌市第三医院,南昌,330009;江西省南昌市第三医院,南昌,330009
摘    要:目的探讨血清白介素-6、8在早期诊断异位妊娠中的作用。方法应用放射免疫法测定异位妊娠患者血清中的白介素-6、8的水平,并与早孕及未孕妇女进行比较,评价其检测的灵敏度、特异性、阳性预测值、阴性预测值。结果异位妊娠组与早孕对照组IL-6、IL-8数据比较均有显著性意义(P〈0.05)。异位妊娠组和早孕对照组血清IL-6、IL-8水平分别与正常未孕妇女组比较有非常显著差异(P〈0.001)。将IL-6和IL-8的阈值定为80pg/ml和130pg/ml,则敏感性分别为58.82%、70.59%,阴性预测值分别是55.32%和65.90%。结论异位妊娠患者血清白细胞介素-6、8水平比正常非孕妇女和正常宫内早孕妇女高,血清白细胞介素-6和白细胞介素-8的测定能够作为诊断早期妊娠、异位妊娠的依据之一。

关 键 词:异位妊娠  白介素-6  白介素-8

Study the value of serum interleukin(IL)-6,IL-8 levels in diagnostic of early ectopic pregnancy
Yang Lijuan,Wang Yongzheng,Zhang Wei,et al.. Study the value of serum interleukin(IL)-6,IL-8 levels in diagnostic of early ectopic pregnancy[J]. Jiangxi Medical Journal, 2009, 44(6): 553-555
Authors:Yang Lijuan  Wang Yongzheng  Zhang Wei  et al.
Affiliation:Yang Lijuan,Wang Yongzheng,Zhang Wei,et al. Department of gynecology , obstetrics,the third hospital of Nanchang,Jiangxi Nanchang 330009,China
Abstract:Objective To evaluate the value of serum interleukin (IL)-6,IL-8 levels in diagnostic of early ectopic pregnancy. Methods The serum Interleu-kin(IL)-6,IL-8 concentration were determined by radioimmunoassay(RIA).51 women with EP, 30 wom- en with normal women,and 45 women with normal intrauterine early pregnancy were compared at stages of gestation. Effects of IL-6, IL8 were studied on the level of severity of the ectopic pregnancy.Diagnostic evaluation of the IL-6,8 was evaluated with sensitivity, specificit...
Keywords:ectopic pregnancy  IL-6  IL-8  
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