Abstract: | The leaves of Mitragyna inermis (Willd.) O. Kuntze have been examined for alkaloids and shown to contain routundifoline, isorotundifoline, rhynchophylline, isorhynchophylline, ciliaphylline, rhynchociline, speciophylline, a small amount of uncarine F, mitraciliatine and traces of a second indole alkaloid which appears to be of the corynanthine type. There is also a polar compound present, Dragendorff positive, which remains on the base line when subjected to thin-layer chromatography with the usual solvent systems used for the mitragyna alkaloids. |