| M2型巨噬细胞标志物CD206与肿瘤 |
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| 引用本文： | 李悦,高磊,李红昌,于宏杰,张勇.M2型巨噬细胞标志物CD206与肿瘤[J].国际肿瘤学杂志,2019,46(3):174-177. |
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| 作者姓名： | 李悦 高磊 李红昌 于宏杰 张勇 |
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| 作者单位： | 上海中医药大学附属普陀医院中心实验室 200333;上海中医药大学附属普陀医院中医肿瘤科 200333 |
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| 基金项目： | 国家自然科学基金(81703881). |
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| 摘 要： | 肿瘤相关巨噬细胞存在于肿瘤进展的所有阶段,起到促进血管生成、组织侵袭等作用,其中以M2型巨噬细胞居多。CD206是M2型巨噬细胞标志物,具有高度特异性,与肿瘤细胞的增殖和转移密不可分。已有研究表明CD206与乳腺癌、卵巢癌、胰腺癌、前列腺癌等恶性肿瘤密切相关,深化对CD206的研究对阐述肿瘤免疫微环境的形成机制、寻找更具针对性的靶向药物有一定的临床指导意义。
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| 关 键 词： | 肿瘤 M2型巨噬细胞 CD206 |
M2 macrophage marker CD206 and tumor |
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| Li Yue,Gao Lei,Li Hongchang,Yu Hongjie,Zhang Yong.M2 macrophage marker CD206 and tumor[J].Journal of International Oncology,2019,46(3):174-177. |
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| Authors: | Li Yue Gao Lei Li Hongchang Yu Hongjie Zhang Yong |
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| Institution: | (Central Laboratory, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200333, China;Department of Traditional Chinese Oncology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200333, China) |
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| Abstract: | Li Yue;Gao Lei;Li Hongchang;Yu Hongjie;Zhang Yong(Central Laboratory, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200333, China;Department of Traditional Chinese Oncology, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200333, China) |
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| Keywords: | Neoplasms M2 macrophage CD206 |
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