Newer aspects of carnitine metabolism in uremia |
| |
| Authors: | Savica Vincenzo Calvani Menotti Benatti Paola Santoro Domenico Monardo Paolo Mallamace Agostino Savica Rodolfo Bellinghieri Guido |
| |
| Affiliation: | Nephrology, University of Messina, Nephrology and Dialysis Units, Papardo Hospital and Policlinic University of Messina, Scientific Department of Sigma-Tau, Rome, Italy. visavica@tin.it |
| |
| Abstract: | New knowledge on the physiologic role of L-carnitine and on the rationale of its use in patients on maintenance hemodialysis is provided. In particular, carnitine normalizes plasma and muscle carnitine levels and modifies both enzymatic pattern of muscle and morphology of single fibers, improving exercise tolerance. In addition, carnitine reduces erythropoietin requirements, the number of hypotensive episodes, improves ejection fraction, and decreases hospitalization. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
