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幼年特发性关节炎诊疗规范
引用本文:李彩凤,黄新翔,王永福,郑朝晖,黄艳艳,张文,赵岩,中华医学会风湿病学分会.幼年特发性关节炎诊疗规范[J].中华内科杂志,2022(2):142-156.
作者姓名:李彩凤  黄新翔  王永福  郑朝晖  黄艳艳  张文  赵岩  中华医学会风湿病学分会
作者单位:国家儿童医学中心;广西医学科学院广西壮族自治区人民医院风湿免疫科;内蒙古科技大学包头医学院第一附属医院风湿免疫科;空军军医大学西京医院临床免疫科;海南省人民医院(海南医学院附属海南医院)风湿免疫科;中国医学科学院
摘    要:幼年特发性关节炎(JIA)临床上常见亚型包括全身型JIA、少关节型/多关节型JIA和幼年脊柱关节炎。本病无特异性诊断指标, 需与感染性疾病和恶性病相鉴别。全身型JIA起病多急骤, 病情进展快, 易合并巨噬细胞活化综合征而危及生命。儿童风湿科医生对JIA的诊断及治疗经验仍不足, 规范化诊疗水平有待进一步提高。中华医学会风湿病学分会组织有关专家, 在借鉴国内外诊疗规范和分类标准的基础上, 制定本规范, 旨在规范JIA各亚型及全身型JIA合并巨噬细胞活化综合征的诊断和治疗方案, 以降低致死率和严重并发症的发生率, 从而改善患儿预后。

关 键 词:幼年特发性关节炎  诊断  治疗  预后

Recommendations of diagnosis and treatment of juvenile idiopathic arthritis in China
Institution:(Department of Rheumatology,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Department of Rheumatology and Immunology,Guangxi Academy of Medical Sciences,the People′s Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,China;Department of Rheumatology and Immunology,the First Affiliated Hospital of Baotou Medical College,Science and Technology University of Inner Mongolia,Baotou 014010,China;Department of Clinical Immunology,Xijing Hospital,the Fourth Military Medical University,Xi′an 710032,China;Department of Rheumatology and Clinical Immunology,Hainan General Hospital(Hainan Affiliated Hospital of Hainan Medical University),Haikou 570311,China;Department of Rheumatology and Clinical Immunology,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,National Clinical Research Center for Dermatologic and Immunologic Diseases,State Key Laboratory of Complex Sever and Rare Diseases,Key Laboratory of Rheumatology and Clinical Immunology,Ministry of Education,Beijing 100730,China;不详)
Abstract:The common clinical subtypes of juvenile idiopathic arthritis(JIA)include systemic onset juvenile idiopathic arthritis(SOJIA),oligoarthritis/polyarthritis juvenile idiopathic arthritis and juvenile spondyloarthritis.Juvenile idiopathic arthritis has no specific diagnostic index,and needs to be differentiated from infectious diseases and malignant diseases.The onset of SOJIA is rapid,the disease progresses rapidly,and it is easy to be complicated with macrophage activation syndrome(MAS)which is life-threatening.The experience of pediatric rheumatologists in dealing with JIA is still insufficient,and the standardized diagnosis and treatment level of this disease needs to be further improved.Based on the experience and guidelines of diagnosis and treatment in China and abroad,we formulated this diagnosis and treatment standard,aiming at standardizing the diagnosis and treatment of the subtypes of JIA and MAS,so as to reduce the incidence of disability and serious complications and improve the prognosis.
Keywords:Juvenile idiopathic arthritis  Diagnosis  Treatments  Prognosis
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